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Developmentally regulated GTP-binding protein 2 coordinates Rab5 activity and transferrin recycling
The small GTPase Rab5 regulates the early endocytic pathway of transferrin (Tfn), and Rab5 deactivation is required for Tfn recycling. Rab5 deactivation is achieved by RabGAP5, a GTPase-activating protein, on the endosomes. Here we report that recruitment of RabGAP5 is insufficient to deactivate Rab...
Autores principales: | Mani, Muralidharan, Lee, Unn Hwa, Yoon, Nal Ae, Kim, Hyo Jeong, Ko, Myoung Seok, Seol, Wongi, Joe, Yeonsoo, Chung, Hun Taeg, Lee, Byung Ju, Moon, Chang Hoon, Cho, Wha Ja, Park, Jeong Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713135/ https://www.ncbi.nlm.nih.gov/pubmed/26582392 http://dx.doi.org/10.1091/mbc.E15-08-0558 |
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