Sequential posttranslational modifications regulate PKC degradation

Cross-talk among different types of posttranslational modifications (PTMs) has emerged as an important regulatory mechanism for protein function. Here we elucidate a mechanism that controls PKCα stability via a sequential cascade of PTMs. We demonstrate that PKCα dephosphorylation decreases its sumo...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Wang, Yangbo, Zhang, Huijun, Gao, Yingwei, Huang, Chao, Zhou, Aiwu, Zhou, Yi, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713141/
https://www.ncbi.nlm.nih.gov/pubmed/26564794
http://dx.doi.org/10.1091/mbc.E15-09-0624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713141/
https://www.ncbi.nlm.nih.gov/pubmed/26564794
http://dx.doi.org/10.1091/mbc.E15-09-0624

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