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Intrinsic Viral Factors Are the Dominant Determinants of the Hepatitis C Virus Response to Interferon Alpha Treatment in Chimeric Mice

BACKGROUND: Hepatitis C virus infection is a global health problem. New direct-acting antiviral agents have been recently approved. However, due to their high cost and some genotypes remaining difficult to treat, interferon-based therapy with pegylated interferon and ribavirin likely may remain a co...

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Detalles Bibliográficos
Autores principales:	Chen, Ran, Kobewka, Michelle, Addison, William, Lachance, Gerald, Tyrrell, D. Lorne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713165/ https://www.ncbi.nlm.nih.gov/pubmed/26765841 http://dx.doi.org/10.1371/journal.pone.0147007

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