A Sensitized Screen for Genes Promoting Invadopodia Function In Vivo: CDC-42 and Rab GDI-1 Direct Distinct Aspects of Invadopodia Formation

Invadopodia are specialized membrane protrusions composed of F-actin, actin regulators, signaling proteins, and a dynamically trafficked invadopodial membrane that drive cell invasion through basement membrane (BM) barriers in development and cancer. Due to the challenges of studying invasion in viv...

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Detalles Bibliográficos
Autores principales: Lohmer, Lauren L., Clay, Matthew R., Naegeli, Kaleb M., Chi, Qiuyi, Ziel, Joshua W., Hagedorn, Elliott J., Park, Jieun E., Jayadev, Ranjay, Sherwood, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713207/
https://www.ncbi.nlm.nih.gov/pubmed/26765257
http://dx.doi.org/10.1371/journal.pgen.1005786

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