Cargando…

The Histone Demethylase PHF8 Is Essential for Endothelial Cell Migration

Epigenetic marks critically control gene expression and thus the cellular activity state. The functions of many epigenetic modifiers in the vascular system have not yet been studied. We screened for histone modifiers in endothelial cells and observed a fairly high expression of the histone plant hom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Lunda, Hitzel, Juliane, Moll, Franziska, Kruse, Christoph, Malik, Randa Abdel, Preussner, Jens, Looso, Mario, Leisegang, Matthias S., Steinhilber, Dieter, Brandes, Ralf P., Fork, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713448/ https://www.ncbi.nlm.nih.gov/pubmed/26751588 http://dx.doi.org/10.1371/journal.pone.0146645

Ejemplares similares

The histone demethylase PHF8 is essential for cytoskeleton dynamics
por: Asensio-Juan, Elena, et al.
Publicado: (2012)

Epigenetic Regulation of Adipogenesis by PHF2 Histone Demethylase
por: Okuno, Yosuke, et al.
Publicado: (2013)

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells
por: Fork, Christian, et al.
Publicado: (2014)

Oncogenic Features of PHF8 Histone Demethylase in Esophageal Squamous Cell Carcinoma
por: Sun, Xiujing, et al.
Publicado: (2013)

Histone demethylase PHF8 promotes epithelial to mesenchymal transition and breast tumorigenesis
por: Shao, Peng, et al.
Publicado: (2017)

The histone demethylase PHF8 is a molecular safeguard of the IFNγ response
por: Asensio-Juan, Elena, et al.
Publicado: (2017)

The histone demethylase PHF8 regulates TGFβ signaling and promotes melanoma metastasis
por: Moubarak, Rana S., et al.
Publicado: (2022)

Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway
por: Chen, Xuemei, et al.
Publicado: (2018)

Histone Demethylase PHF8 Is Required for the Development of the Zebrafish Inner Ear and Posterior Lateral Line
por: He, Jing, et al.
Publicado: (2020)

The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells
por: Pflüger-Müller, Beatrice, et al.
Publicado: (2020)

The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity
por: Bricambert, Julien, et al.
Publicado: (2018)

Histone demethylase PHF8 drives neuroendocrine prostate cancer progression by epigenetically upregulating FOXA2
por: Liu, Qiuli, et al.
Publicado: (2020)

Histone demethylase PHF8 accelerates the progression of colorectal cancer and can be regulated by miR-488 in vitro
por: Lv, Yao, et al.
Publicado: (2017)

Commentary: The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity
por: Barbaro, Barbara, et al.
Publicado: (2018)

c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer
por: Maina, Peterson Kariuki, et al.
Publicado: (2016)

Essential Functions of the Histone Demethylase Lid
por: Li, Ling, et al.
Publicado: (2010)

A Functional Link between the Histone Demethylase PHF8 and the Transcription Factor ZNF711 in X-Linked Mental Retardation
por: Kleine-Kohlbrecher, Daniela, et al.
Publicado: (2010)

The histone demethylase PHF8 promotes prostate cancer cell growth by activating the oncomiR miR-125b
por: Ma, Qiang, et al.
Publicado: (2015)

Targeting the histone demethylase PHF8-mediated PKCα-Src-PTEN axis in HER2-negative gastric cancer
por: Tseng, Lin-Lu, et al.
Publicado: (2020)

The Histone Demethylase PHF2 Promotes Fat Cell Differentiation as an Epigenetic Activator of Both C/EBPα and C/EBPδ
por: Lee, Kyoung-Hwa, et al.
Publicado: (2014)

Histone demethylase PHF8 regulates hypoxia signaling through HIF1α and H3K4me3
por: Maina, Peterson Kariuki, et al.
Publicado: (2017)

Catalysis by the Non-Heme Iron(II) Histone Demethylase PHF8 Involves Iron Center Rearrangement and Conformational Modulation of Substrate Orientation
por: Chaturvedi, Shobhit S., et al.
Publicado: (2019)

The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila
por: Drelon, Coralie, et al.
Publicado: (2018)

The histone demethylase Kdm3a is essential to progression through differentiation
por: Herzog, Marielle, et al.
Publicado: (2012)

Histone demethylase lysine demethylase 5B in development and cancer
por: Han, Mengjiao, et al.
Publicado: (2016)

The XLMR gene PHF8 encodes a histone H4K20/H3K9 demethylase and regulates zebrafish brain and craniofacial development
por: Qi, Hank H., et al.
Publicado: (2010)

Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19
por: Dong, Cheng, et al.
Publicado: (2020)

Histone Demethylase Activity of Utx Is Essential for Viability and Regulation of HOX Gene Expression in Drosophila
por: Copur, Ömer, et al.
Publicado: (2018)

Histone demethylases in chromatin biology and beyond
por: Dimitrova, Emilia, et al.
Publicado: (2015)

Histone lysine demethylases in Drosophila melanogaster
por: Holowatyj, Andreana, et al.
Publicado: (2015)

Histone demethylases in the regulation of immunity and inflammation
por: Qu, Lihua, et al.
Publicado: (2023)

The Histone Demethylase Activity of Rph1 is Not Essential for Its Role in the Transcriptional Response to Nutrient Signaling
por: Nordberg, Niklas, et al.
Publicado: (2014)

Essential Roles of the Histone Demethylase KDM4C in Renal Development and Acute Kidney Injury
por: Pan, Heng-Chih, et al.
Publicado: (2022)

Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function
por: Leisegang, Matthias S., et al.
Publicado: (2017)

Role of Histone Demethylases in Cardiomyocytes Induced to Hypertrophy
por: Rosales, Wendy, et al.
Publicado: (2016)

Histone lysine demethylases in mammalian embryonic development
por: Shen, Hongjie, et al.
Publicado: (2017)

ETS transcription factor ERG cooperates with histone demethylase KDM4A
por: KIM, TAE-DONG, et al.
Publicado: (2016)

Control of Breast Cancer Pathogenesis by Histone Methylation and the Hairless Histone Demethylase
por: Trager, Megan H, et al.
Publicado: (2021)

Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14
por: Zheng, Shuangping, et al.
Publicado: (2021)

Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM)
por: Lapidot, Moshe, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0qn65vamh800vr6gm71n7r81s7