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WNT-5A: signaling and functions in health and disease

WNT-5A plays critical roles in a myriad of processes from embryonic morphogenesis to the maintenance of post-natal homeostasis. WNT-5A knock-out mice fail to survive and present extensive structural malformations. WNT-5A predominantly activates β-catenin-independent WNT signaling cascade but can als...

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Detalles Bibliográficos
Autores principales: Kumawat, Kuldeep, Gosens, Reinoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713724/
https://www.ncbi.nlm.nih.gov/pubmed/26514730
http://dx.doi.org/10.1007/s00018-015-2076-y

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