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WNT-5A: signaling and functions in health and disease
WNT-5A plays critical roles in a myriad of processes from embryonic morphogenesis to the maintenance of post-natal homeostasis. WNT-5A knock-out mice fail to survive and present extensive structural malformations. WNT-5A predominantly activates β-catenin-independent WNT signaling cascade but can als...
Autores principales: | Kumawat, Kuldeep, Gosens, Reinoud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713724/ https://www.ncbi.nlm.nih.gov/pubmed/26514730 http://dx.doi.org/10.1007/s00018-015-2076-y |
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