Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination

Remyelination in multiple sclerosis (MS) lesions often remains incomplete despite the presence of oligodendrocyte progenitor cells (OPCs). Amongst other factors, successful remyelination depends on the phagocytic clearance of myelin debris. However, the proteins in myelin debris that act as potent a...

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Detalles Bibliográficos
Autores principales: Syed, Yasir A., Zhao, Chao, Mahad, Don, Möbius, Wiebke, Altmann, Friedrich, Foss, Franziska, Sentürk, Aycan, Acker-Palmer, Amparo, Lubec, Gert, Lilley, Kathryn, Franklin, Robin J. M., Nave, Klaus-A., Kotter, Mark R. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713754/
https://www.ncbi.nlm.nih.gov/pubmed/26687980
http://dx.doi.org/10.1007/s00401-015-1521-1

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