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Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis
BACKGROUND & AIMS: Insulin resistance and lipotoxicity are pathognomonic in non-alcoholic steatohepatitis (NASH). Glucagon-like peptide-1 (GLP-1) analogues are licensed for type 2 diabetes, but no prospective experimental data exists in NASH. This study determined the effect of a long-acting GLP...
Autores principales: | Armstrong, Matthew J., Hull, Diana, Guo, Kathy, Barton, Darren, Hazlehurst, Jonathan M., Gathercole, Laura L., Nasiri, Maryam, Yu, Jinglei, Gough, Stephen C., Newsome, Philip N., Tomlinson, Jeremy W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713865/ https://www.ncbi.nlm.nih.gov/pubmed/26394161 http://dx.doi.org/10.1016/j.jhep.2015.08.038 |
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