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Propofol Pharmacokinetics and Estimation of Fetal Propofol Exposure during Mid-Gestational Fetal Surgery: A Maternal-Fetal Sheep Model

BACKGROUND: Measuring fetal drug concentrations is extremely difficult in humans. We conducted a study in pregnant sheep to simultaneously describe maternal and fetal concentrations of propofol, a common intravenous anesthetic agent used in humans. Compared to inhalational anesthesia, propofol suppl...

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Detalles Bibliográficos
Autores principales:	Ngamprasertwong, Pornswan, Dong, Min, Niu, Jing, Venkatasubramanian, Raja, Vinks, Alexander A., Sadhasivam, Senthilkumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713870/ https://www.ncbi.nlm.nih.gov/pubmed/26752560 http://dx.doi.org/10.1371/journal.pone.0146563

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