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Effects of Toll-like receptor antagonist 4,5-dihydro-3-phenyl-5-isoxasole acetic acid on the progression of kidney disease in mice on a high-fat diet

BACKGROUND: Obesity-related metabolic disorders are closely associated with inflammation induced by innate immunity. Toll-like receptors (TLRs) play a pivotal role in the innate immune system by activating proinflammatory signaling pathways. GIT27 (4,5-dihydro-3-phenyl-5-isoxasole acetic acid) is an...

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Detalles Bibliográficos
Autores principales:	Min, Hye Sook, Kim, Jung Eun, Lee, Mi Hwa, Song, Hye Kyoung, Lee, Mi Jin, Lee, Ji Eun, Kim, Hyun Wook, Cha, Jin Joo, Hyun, Young Youl, Han, Jee Young, Cha, Dae Ryong, Kang, Young Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714156/ https://www.ncbi.nlm.nih.gov/pubmed/26877948 http://dx.doi.org/10.1016/j.krcp.2013.11.002

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