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Prostate Cancer and Li-Fraumeni Syndrome: Implications for Screening and Therapy

Li-Fraumeni Syndrome (LFS) is an autosomal dominant genetic disorder associated with mutations in the TP53 gene and characterized by a propensity to develop a variety of malignancies resulting in a shortened lifespan. We report a case of prostate cancer in a 50 year old male with LFS. Experimental s...

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Detalles Bibliográficos
Autores principales: Spees, Colleen K., Kelleher, Kelly J., Abaza, Ronney, Clinton, Steven K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714266/
https://www.ncbi.nlm.nih.gov/pubmed/26793489
http://dx.doi.org/10.1016/j.eucr.2015.01.002

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