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Prostate Cancer and Li-Fraumeni Syndrome: Implications for Screening and Therapy
Li-Fraumeni Syndrome (LFS) is an autosomal dominant genetic disorder associated with mutations in the TP53 gene and characterized by a propensity to develop a variety of malignancies resulting in a shortened lifespan. We report a case of prostate cancer in a 50 year old male with LFS. Experimental s...
Autores principales: | Spees, Colleen K., Kelleher, Kelly J., Abaza, Ronney, Clinton, Steven K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714266/ https://www.ncbi.nlm.nih.gov/pubmed/26793489 http://dx.doi.org/10.1016/j.eucr.2015.01.002 |
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