A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab

A 68-year-old man was introduced to our hospital for the treatment of lung and mediastinum lymph node metastases that originated from an urachal carcinoma 4 years after a partial cystectomy. First-line chemotherapy with an S-1 and cisplatin combination was ineffective. The patient received FOLFIRI p...

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Autores principales: Kanamaru, Tomohiro, Iguchi, Taro, Yukimatsu, Nao, Shimizu, Yasuomi, Kohyama, Yuki, Tachibana, Hirokazu, Kato, Minoru, Yamasaki, Takeshi, Tamada, Satoshi, Nakatani, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714276/
https://www.ncbi.nlm.nih.gov/pubmed/26793485
http://dx.doi.org/10.1016/j.eucr.2014.11.004
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author Kanamaru, Tomohiro
Iguchi, Taro
Yukimatsu, Nao
Shimizu, Yasuomi
Kohyama, Yuki
Tachibana, Hirokazu
Kato, Minoru
Yamasaki, Takeshi
Tamada, Satoshi
Nakatani, Tatsuya
author_facet Kanamaru, Tomohiro
Iguchi, Taro
Yukimatsu, Nao
Shimizu, Yasuomi
Kohyama, Yuki
Tachibana, Hirokazu
Kato, Minoru
Yamasaki, Takeshi
Tamada, Satoshi
Nakatani, Tatsuya
author_sort Kanamaru, Tomohiro
collection PubMed
description A 68-year-old man was introduced to our hospital for the treatment of lung and mediastinum lymph node metastases that originated from an urachal carcinoma 4 years after a partial cystectomy. First-line chemotherapy with an S-1 and cisplatin combination was ineffective. The patient received FOLFIRI plus bevacizumab chemotherapy as salvage chemotherapy. Stability was achieved after eight cycles of FOLFIRI plus bevacizumab therapy. We conducted a biopsy of the metastatic tumor, and the pathology of the biopsy tissue was partially necrotic. To our knowledge, this case represents the first report of a metastatic urachal carcinoma treated with FOLFIRI plus bevacizumab.
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spelling pubmed-47142762016-01-20 A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab Kanamaru, Tomohiro Iguchi, Taro Yukimatsu, Nao Shimizu, Yasuomi Kohyama, Yuki Tachibana, Hirokazu Kato, Minoru Yamasaki, Takeshi Tamada, Satoshi Nakatani, Tatsuya Urol Case Rep Oncology A 68-year-old man was introduced to our hospital for the treatment of lung and mediastinum lymph node metastases that originated from an urachal carcinoma 4 years after a partial cystectomy. First-line chemotherapy with an S-1 and cisplatin combination was ineffective. The patient received FOLFIRI plus bevacizumab chemotherapy as salvage chemotherapy. Stability was achieved after eight cycles of FOLFIRI plus bevacizumab therapy. We conducted a biopsy of the metastatic tumor, and the pathology of the biopsy tissue was partially necrotic. To our knowledge, this case represents the first report of a metastatic urachal carcinoma treated with FOLFIRI plus bevacizumab. Elsevier 2014-12-23 /pmc/articles/PMC4714276/ /pubmed/26793485 http://dx.doi.org/10.1016/j.eucr.2014.11.004 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Oncology
Kanamaru, Tomohiro
Iguchi, Taro
Yukimatsu, Nao
Shimizu, Yasuomi
Kohyama, Yuki
Tachibana, Hirokazu
Kato, Minoru
Yamasaki, Takeshi
Tamada, Satoshi
Nakatani, Tatsuya
A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab
title A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab
title_full A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab
title_fullStr A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab
title_full_unstemmed A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab
title_short A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab
title_sort case of metastatic urachal carcinoma treated with folfiri (irinotecan and 5-fluorouracil/leucovorin) plus bevacizumab
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714276/
https://www.ncbi.nlm.nih.gov/pubmed/26793485
http://dx.doi.org/10.1016/j.eucr.2014.11.004
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