Cargando…
Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait
Medullary carcinoma is a rare malignant tumor of the kidney. It affects individuals of African descent and all cases reported show evidence of sickle cell trait. We reviewed an unusual carcinoma arising in a white man, the ninth in the literature. The tumor demonstrated features associated with rena...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714316/ https://www.ncbi.nlm.nih.gov/pubmed/26793557 http://dx.doi.org/10.1016/j.eucr.2015.07.011 |
_version_ | 1782410295325491200 |
---|---|
author | Colombo, Piergiuseppe Smith, Steven C. Massa, Simona Renne, Salvatore L. Brambilla, Simona Peschechera, Roberto Graziotti, Pierpaolo Roncalli, Massimo Amin, Mahul B. |
author_facet | Colombo, Piergiuseppe Smith, Steven C. Massa, Simona Renne, Salvatore L. Brambilla, Simona Peschechera, Roberto Graziotti, Pierpaolo Roncalli, Massimo Amin, Mahul B. |
author_sort | Colombo, Piergiuseppe |
collection | PubMed |
description | Medullary carcinoma is a rare malignant tumor of the kidney. It affects individuals of African descent and all cases reported show evidence of sickle cell trait. We reviewed an unusual carcinoma arising in a white man, the ninth in the literature. The tumor demonstrated features associated with renal medullary carcinoma, or unclassified renal cell carcinoma, medullary phenotype as recently described; the presence of sickle cell trait confirmed the diagnosis of medullary carcinoma. This case is helpful in the differential diagnosis with non-sickle cell associated “renal cell carcinoma, unclassified with medullary phenotype,” and study of this spectrum of tumors is ongoing. |
format | Online Article Text |
id | pubmed-4714316 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-47143162016-01-20 Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait Colombo, Piergiuseppe Smith, Steven C. Massa, Simona Renne, Salvatore L. Brambilla, Simona Peschechera, Roberto Graziotti, Pierpaolo Roncalli, Massimo Amin, Mahul B. Urol Case Rep Oncology Medullary carcinoma is a rare malignant tumor of the kidney. It affects individuals of African descent and all cases reported show evidence of sickle cell trait. We reviewed an unusual carcinoma arising in a white man, the ninth in the literature. The tumor demonstrated features associated with renal medullary carcinoma, or unclassified renal cell carcinoma, medullary phenotype as recently described; the presence of sickle cell trait confirmed the diagnosis of medullary carcinoma. This case is helpful in the differential diagnosis with non-sickle cell associated “renal cell carcinoma, unclassified with medullary phenotype,” and study of this spectrum of tumors is ongoing. Elsevier 2015-09-05 /pmc/articles/PMC4714316/ /pubmed/26793557 http://dx.doi.org/10.1016/j.eucr.2015.07.011 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Oncology Colombo, Piergiuseppe Smith, Steven C. Massa, Simona Renne, Salvatore L. Brambilla, Simona Peschechera, Roberto Graziotti, Pierpaolo Roncalli, Massimo Amin, Mahul B. Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait |
title | Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait |
title_full | Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait |
title_fullStr | Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait |
title_full_unstemmed | Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait |
title_short | Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait |
title_sort | unclassified renal cell carcinoma with medullary phenotype versus renal medullary carcinoma: lessons from diagnosis in an italian man found to harbor sickle cell trait |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714316/ https://www.ncbi.nlm.nih.gov/pubmed/26793557 http://dx.doi.org/10.1016/j.eucr.2015.07.011 |
work_keys_str_mv | AT colombopiergiuseppe unclassifiedrenalcellcarcinomawithmedullaryphenotypeversusrenalmedullarycarcinomalessonsfromdiagnosisinanitalianmanfoundtoharborsicklecelltrait AT smithstevenc unclassifiedrenalcellcarcinomawithmedullaryphenotypeversusrenalmedullarycarcinomalessonsfromdiagnosisinanitalianmanfoundtoharborsicklecelltrait AT massasimona unclassifiedrenalcellcarcinomawithmedullaryphenotypeversusrenalmedullarycarcinomalessonsfromdiagnosisinanitalianmanfoundtoharborsicklecelltrait AT rennesalvatorel unclassifiedrenalcellcarcinomawithmedullaryphenotypeversusrenalmedullarycarcinomalessonsfromdiagnosisinanitalianmanfoundtoharborsicklecelltrait AT brambillasimona unclassifiedrenalcellcarcinomawithmedullaryphenotypeversusrenalmedullarycarcinomalessonsfromdiagnosisinanitalianmanfoundtoharborsicklecelltrait AT peschecheraroberto unclassifiedrenalcellcarcinomawithmedullaryphenotypeversusrenalmedullarycarcinomalessonsfromdiagnosisinanitalianmanfoundtoharborsicklecelltrait AT graziottipierpaolo unclassifiedrenalcellcarcinomawithmedullaryphenotypeversusrenalmedullarycarcinomalessonsfromdiagnosisinanitalianmanfoundtoharborsicklecelltrait AT roncallimassimo unclassifiedrenalcellcarcinomawithmedullaryphenotypeversusrenalmedullarycarcinomalessonsfromdiagnosisinanitalianmanfoundtoharborsicklecelltrait AT aminmahulb unclassifiedrenalcellcarcinomawithmedullaryphenotypeversusrenalmedullarycarcinomalessonsfromdiagnosisinanitalianmanfoundtoharborsicklecelltrait |