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Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait

Medullary carcinoma is a rare malignant tumor of the kidney. It affects individuals of African descent and all cases reported show evidence of sickle cell trait. We reviewed an unusual carcinoma arising in a white man, the ninth in the literature. The tumor demonstrated features associated with rena...

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Autores principales: Colombo, Piergiuseppe, Smith, Steven C., Massa, Simona, Renne, Salvatore L., Brambilla, Simona, Peschechera, Roberto, Graziotti, Pierpaolo, Roncalli, Massimo, Amin, Mahul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714316/
https://www.ncbi.nlm.nih.gov/pubmed/26793557
http://dx.doi.org/10.1016/j.eucr.2015.07.011
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author Colombo, Piergiuseppe
Smith, Steven C.
Massa, Simona
Renne, Salvatore L.
Brambilla, Simona
Peschechera, Roberto
Graziotti, Pierpaolo
Roncalli, Massimo
Amin, Mahul B.
author_facet Colombo, Piergiuseppe
Smith, Steven C.
Massa, Simona
Renne, Salvatore L.
Brambilla, Simona
Peschechera, Roberto
Graziotti, Pierpaolo
Roncalli, Massimo
Amin, Mahul B.
author_sort Colombo, Piergiuseppe
collection PubMed
description Medullary carcinoma is a rare malignant tumor of the kidney. It affects individuals of African descent and all cases reported show evidence of sickle cell trait. We reviewed an unusual carcinoma arising in a white man, the ninth in the literature. The tumor demonstrated features associated with renal medullary carcinoma, or unclassified renal cell carcinoma, medullary phenotype as recently described; the presence of sickle cell trait confirmed the diagnosis of medullary carcinoma. This case is helpful in the differential diagnosis with non-sickle cell associated “renal cell carcinoma, unclassified with medullary phenotype,” and study of this spectrum of tumors is ongoing.
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spelling pubmed-47143162016-01-20 Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait Colombo, Piergiuseppe Smith, Steven C. Massa, Simona Renne, Salvatore L. Brambilla, Simona Peschechera, Roberto Graziotti, Pierpaolo Roncalli, Massimo Amin, Mahul B. Urol Case Rep Oncology Medullary carcinoma is a rare malignant tumor of the kidney. It affects individuals of African descent and all cases reported show evidence of sickle cell trait. We reviewed an unusual carcinoma arising in a white man, the ninth in the literature. The tumor demonstrated features associated with renal medullary carcinoma, or unclassified renal cell carcinoma, medullary phenotype as recently described; the presence of sickle cell trait confirmed the diagnosis of medullary carcinoma. This case is helpful in the differential diagnosis with non-sickle cell associated “renal cell carcinoma, unclassified with medullary phenotype,” and study of this spectrum of tumors is ongoing. Elsevier 2015-09-05 /pmc/articles/PMC4714316/ /pubmed/26793557 http://dx.doi.org/10.1016/j.eucr.2015.07.011 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Colombo, Piergiuseppe
Smith, Steven C.
Massa, Simona
Renne, Salvatore L.
Brambilla, Simona
Peschechera, Roberto
Graziotti, Pierpaolo
Roncalli, Massimo
Amin, Mahul B.
Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait
title Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait
title_full Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait
title_fullStr Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait
title_full_unstemmed Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait
title_short Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait
title_sort unclassified renal cell carcinoma with medullary phenotype versus renal medullary carcinoma: lessons from diagnosis in an italian man found to harbor sickle cell trait
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714316/
https://www.ncbi.nlm.nih.gov/pubmed/26793557
http://dx.doi.org/10.1016/j.eucr.2015.07.011
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