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Successful management of malignant hyperpyrexia syndrome in a pediatric patient: What to do when dantrolene is not available?

Malignant hyperpyrexia syndrome (MHS) is a rare entity and may not be encountered by the anaesthesiologists throughout their professional career. Whenever it manifests can be a challenging task to manage and prove to be fatal when a timely diagnosis and required therapeutic measures are not taken. A...

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Autores principales: Gupta, Priyanka, Kamal, Geeta, Gupta, Mayank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714388/
https://www.ncbi.nlm.nih.gov/pubmed/26816473
http://dx.doi.org/10.4103/0976-500X.171873
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author Gupta, Priyanka
Kamal, Geeta
Gupta, Mayank
author_facet Gupta, Priyanka
Kamal, Geeta
Gupta, Mayank
author_sort Gupta, Priyanka
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description Malignant hyperpyrexia syndrome (MHS) is a rare entity and may not be encountered by the anaesthesiologists throughout their professional career. Whenever it manifests can be a challenging task to manage and prove to be fatal when a timely diagnosis and required therapeutic measures are not taken. Althoughthe dantrolene should be available wherever anaesthesia is practiced, considering the rarity of the syndrome this may not be the scenario always. We are reporting a case of MHS in a pediatric patient to highlight the facts that prompt clinical diagnosis, ongoing supportive treatment, discontinuation of all the anaesthetic agents and and stringent perioperative monitoring along with postoperative oral dantrolene may provide an answer to the MHS crisis in the face of an unavailability of the IV dantrolene; as may be the case in many rural and developing set-ups.
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spelling pubmed-47143882016-01-26 Successful management of malignant hyperpyrexia syndrome in a pediatric patient: What to do when dantrolene is not available? Gupta, Priyanka Kamal, Geeta Gupta, Mayank J Pharmacol Pharmacother Case Report Malignant hyperpyrexia syndrome (MHS) is a rare entity and may not be encountered by the anaesthesiologists throughout their professional career. Whenever it manifests can be a challenging task to manage and prove to be fatal when a timely diagnosis and required therapeutic measures are not taken. Althoughthe dantrolene should be available wherever anaesthesia is practiced, considering the rarity of the syndrome this may not be the scenario always. We are reporting a case of MHS in a pediatric patient to highlight the facts that prompt clinical diagnosis, ongoing supportive treatment, discontinuation of all the anaesthetic agents and and stringent perioperative monitoring along with postoperative oral dantrolene may provide an answer to the MHS crisis in the face of an unavailability of the IV dantrolene; as may be the case in many rural and developing set-ups. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4714388/ /pubmed/26816473 http://dx.doi.org/10.4103/0976-500X.171873 Text en Copyright: © Journal of Pharmacology and Pharmacotherapeutics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Gupta, Priyanka
Kamal, Geeta
Gupta, Mayank
Successful management of malignant hyperpyrexia syndrome in a pediatric patient: What to do when dantrolene is not available?
title Successful management of malignant hyperpyrexia syndrome in a pediatric patient: What to do when dantrolene is not available?
title_full Successful management of malignant hyperpyrexia syndrome in a pediatric patient: What to do when dantrolene is not available?
title_fullStr Successful management of malignant hyperpyrexia syndrome in a pediatric patient: What to do when dantrolene is not available?
title_full_unstemmed Successful management of malignant hyperpyrexia syndrome in a pediatric patient: What to do when dantrolene is not available?
title_short Successful management of malignant hyperpyrexia syndrome in a pediatric patient: What to do when dantrolene is not available?
title_sort successful management of malignant hyperpyrexia syndrome in a pediatric patient: what to do when dantrolene is not available?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714388/
https://www.ncbi.nlm.nih.gov/pubmed/26816473
http://dx.doi.org/10.4103/0976-500X.171873
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