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Carbamazepine-induced hypertension: A rare case

A 74-year-old female with trigeminal neuralgia developed hypertension after the initiation of carbamazepine therapy. The time sequence of start of the suspected drug and onset of hypertension are consistent with the diagnosis. The hypertension did not resolve with antihypertensive therapy or dose re...

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Detalles Bibliográficos
Autores principales: Kharb, Preeti, Mittal, Niti, Gupta, Mahesh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714390/
https://www.ncbi.nlm.nih.gov/pubmed/26816475
http://dx.doi.org/10.4103/0976-500X.171879
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author Kharb, Preeti
Mittal, Niti
Gupta, Mahesh C.
author_facet Kharb, Preeti
Mittal, Niti
Gupta, Mahesh C.
author_sort Kharb, Preeti
collection PubMed
description A 74-year-old female with trigeminal neuralgia developed hypertension after the initiation of carbamazepine therapy. The time sequence of start of the suspected drug and onset of hypertension are consistent with the diagnosis. The hypertension did not resolve with antihypertensive therapy or dose reduction of carbamazepine. Patient recovered after the carbamazepine therapy was discontinued. The positive rechallenge and positive dechallenge showed association of carbamazepine therapy with hypertension as its adverse effect. This is a rare case that we report of carbamazepine-induced hypertension and this report may act as alerting mechanism to the health care professionals especially neurologists.
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spelling pubmed-47143902016-01-26 Carbamazepine-induced hypertension: A rare case Kharb, Preeti Mittal, Niti Gupta, Mahesh C. J Pharmacol Pharmacother Case Report A 74-year-old female with trigeminal neuralgia developed hypertension after the initiation of carbamazepine therapy. The time sequence of start of the suspected drug and onset of hypertension are consistent with the diagnosis. The hypertension did not resolve with antihypertensive therapy or dose reduction of carbamazepine. Patient recovered after the carbamazepine therapy was discontinued. The positive rechallenge and positive dechallenge showed association of carbamazepine therapy with hypertension as its adverse effect. This is a rare case that we report of carbamazepine-induced hypertension and this report may act as alerting mechanism to the health care professionals especially neurologists. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4714390/ /pubmed/26816475 http://dx.doi.org/10.4103/0976-500X.171879 Text en Copyright: © Journal of Pharmacology and Pharmacotherapeutics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Kharb, Preeti
Mittal, Niti
Gupta, Mahesh C.
Carbamazepine-induced hypertension: A rare case
title Carbamazepine-induced hypertension: A rare case
title_full Carbamazepine-induced hypertension: A rare case
title_fullStr Carbamazepine-induced hypertension: A rare case
title_full_unstemmed Carbamazepine-induced hypertension: A rare case
title_short Carbamazepine-induced hypertension: A rare case
title_sort carbamazepine-induced hypertension: a rare case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714390/
https://www.ncbi.nlm.nih.gov/pubmed/26816475
http://dx.doi.org/10.4103/0976-500X.171879
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