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Lrp5/6 are required for cerebellar development and for suppressing TH expression in Purkinje cells via β-catenin
BACKGROUND: The cerebellum is responsible for coordinating motor functions and has a unique laminated architecture. Purkinje cells are inhibitory neurons and represent the only output from the cerebellar cortex. Tyrosine hydroxylase (TH) is the key enzyme for the synthesis of catecholamines, includi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714458/ https://www.ncbi.nlm.nih.gov/pubmed/26772978 http://dx.doi.org/10.1186/s13041-015-0183-1 |