Lrp5/6 are required for cerebellar development and for suppressing TH expression in Purkinje cells via β-catenin

BACKGROUND: The cerebellum is responsible for coordinating motor functions and has a unique laminated architecture. Purkinje cells are inhibitory neurons and represent the only output from the cerebellar cortex. Tyrosine hydroxylase (TH) is the key enzyme for the synthesis of catecholamines, includi...

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Detalles Bibliográficos
Autores principales: Huang, Ying, Zhang, Qiong, Song, Ning-Ning, Zhang, Lei, Sun, Yu-Ling, Hu, Ling, Chen, Jia-Ying, Zhu, Weidong, Li, Jue, Ding, Yu-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714458/
https://www.ncbi.nlm.nih.gov/pubmed/26772978
http://dx.doi.org/10.1186/s13041-015-0183-1

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