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Surgery for retrohepatic caval thrombus in patients with advanced renal cell carcinoma: a case series

BACKGROUND: Thrombotic involvement of the inferior vena cava (IVC) occurs in about 10 % of all patients with renal cell carcinoma (RCC). It is treated with radical resection of tumor and thrombus. We present the results of a recent case series of 20 patients with retrohepatic IVC thrombus. METHODS:...

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Autores principales: Polańska-Płachta, Małgorzata, Proczka, Robert, Dudek, Magdalena, Ostrowska, Małgorzata, Polański, Jerzy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714474/
https://www.ncbi.nlm.nih.gov/pubmed/26769197
http://dx.doi.org/10.1186/s12957-015-0765-5
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author Polańska-Płachta, Małgorzata
Proczka, Robert
Dudek, Magdalena
Ostrowska, Małgorzata
Polański, Jerzy A.
author_facet Polańska-Płachta, Małgorzata
Proczka, Robert
Dudek, Magdalena
Ostrowska, Małgorzata
Polański, Jerzy A.
author_sort Polańska-Płachta, Małgorzata
collection PubMed
description BACKGROUND: Thrombotic involvement of the inferior vena cava (IVC) occurs in about 10 % of all patients with renal cell carcinoma (RCC). It is treated with radical resection of tumor and thrombus. We present the results of a recent case series of 20 patients with retrohepatic IVC thrombus. METHODS: Our cohort of 20 patients included 16 primary resections (radical nephrectomy and thrombectomy with and without vascular graft), three recurrences primarily operated on elsewhere (thrombectomy and vascular graft), and one recurrence due to a new liver metastasis. RESULTS: All surviving patients were discharged with a patent IVC. The overall mortality rate was 10 %, and the overall complication rate was 35 %. Both are in keeping with results presented worldwide. CONCLUSIONS: Our series provides a corroborating extension to the existing dataset on RCC-related IVC thrombus removal. It confirms that the radical surgical approach can be performed safely and successfully with respect to venous patency.
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spelling pubmed-47144742016-01-16 Surgery for retrohepatic caval thrombus in patients with advanced renal cell carcinoma: a case series Polańska-Płachta, Małgorzata Proczka, Robert Dudek, Magdalena Ostrowska, Małgorzata Polański, Jerzy A. World J Surg Oncol Research BACKGROUND: Thrombotic involvement of the inferior vena cava (IVC) occurs in about 10 % of all patients with renal cell carcinoma (RCC). It is treated with radical resection of tumor and thrombus. We present the results of a recent case series of 20 patients with retrohepatic IVC thrombus. METHODS: Our cohort of 20 patients included 16 primary resections (radical nephrectomy and thrombectomy with and without vascular graft), three recurrences primarily operated on elsewhere (thrombectomy and vascular graft), and one recurrence due to a new liver metastasis. RESULTS: All surviving patients were discharged with a patent IVC. The overall mortality rate was 10 %, and the overall complication rate was 35 %. Both are in keeping with results presented worldwide. CONCLUSIONS: Our series provides a corroborating extension to the existing dataset on RCC-related IVC thrombus removal. It confirms that the radical surgical approach can be performed safely and successfully with respect to venous patency. BioMed Central 2016-01-15 /pmc/articles/PMC4714474/ /pubmed/26769197 http://dx.doi.org/10.1186/s12957-015-0765-5 Text en © Polańska-Płachta et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Polańska-Płachta, Małgorzata
Proczka, Robert
Dudek, Magdalena
Ostrowska, Małgorzata
Polański, Jerzy A.
Surgery for retrohepatic caval thrombus in patients with advanced renal cell carcinoma: a case series
title Surgery for retrohepatic caval thrombus in patients with advanced renal cell carcinoma: a case series
title_full Surgery for retrohepatic caval thrombus in patients with advanced renal cell carcinoma: a case series
title_fullStr Surgery for retrohepatic caval thrombus in patients with advanced renal cell carcinoma: a case series
title_full_unstemmed Surgery for retrohepatic caval thrombus in patients with advanced renal cell carcinoma: a case series
title_short Surgery for retrohepatic caval thrombus in patients with advanced renal cell carcinoma: a case series
title_sort surgery for retrohepatic caval thrombus in patients with advanced renal cell carcinoma: a case series
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714474/
https://www.ncbi.nlm.nih.gov/pubmed/26769197
http://dx.doi.org/10.1186/s12957-015-0765-5
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