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Piwi-interacting RNAs in cancer: emerging functions and clinical utility

PIWI-interacting RNAs (piRNAs) are emerging players in cancer genomics. Originally described in the germline, there are over 20,000 piRNA genes in the human genome. In contrast to microRNAs, piRNAs interact with PIWI proteins, another member of the Argonaute family, and function primarily in the nuc...

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Detalles Bibliográficos
Autores principales:	Ng, Kevin W., Anderson, Christine, Marshall, Erin A., Minatel, Brenda C., Enfield, Katey S. S., Saprunoff, Heather L., Lam, Wan L., Martinez, Victor D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714483/ https://www.ncbi.nlm.nih.gov/pubmed/26768585 http://dx.doi.org/10.1186/s12943-016-0491-9

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