Permanent draft genome sequence of the probiotic strain Propionibacterium freudenreichii CIRM-BIA 129 (ITG P20)

Propionibacterium freudenreichii belongs to the class Actinobacteria (Gram positive with a high GC content). This “Generally Recognized As Safe” (GRAS) species is traditionally used as (i) a starter for Swiss-type cheeses where it is responsible for holes and aroma production, (ii) a vitamin B12 and...

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Detalles Bibliográficos
Autores principales: Falentin, Hélène, Deutsch, Stéphanie-Marie, Loux, Valentin, Hammani, Amal, Buratti, Julien, Parayre, Sandrine, Chuat, Victoria, Barbe, Valérie, Aury, Jean-Marc, Jan, Gwenaël, Le Loir, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Short Genome Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714504/
https://www.ncbi.nlm.nih.gov/pubmed/26779303
http://dx.doi.org/10.1186/s40793-015-0120-z
Descripción
Sumario:Propionibacterium freudenreichii belongs to the class Actinobacteria (Gram positive with a high GC content). This “Generally Recognized As Safe” (GRAS) species is traditionally used as (i) a starter for Swiss-type cheeses where it is responsible for holes and aroma production, (ii) a vitamin B12 and propionic acid producer in white biotechnologies, and (iii) a probiotic for use in humans and animals because of its bifidogenic and anti-inflammatory properties. Until now, only strain CIRM-BIA1T had been sequenced, annotated and become publicly available. Strain CIRM-BIA129 (commercially available as ITG P20) has considerable anti-inflammatory potential. Its gene content was compared to that of CIRM-BIA1 T. This strain contains 2384 genes including 1 ribosomal operon, 45 tRNA and 30 pseudogenes.

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