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Store depletion induces Gαq-mediated PLCβ1 activity to stimulate TRPC1 channels in vascular smooth muscle cells
Depletion of sarcoplasmic reticulum (SR) Ca(2+) stores activates store-operated channels (SOCs) composed of canonical transient receptor potential (TRPC) 1 proteins in vascular smooth muscle cells (VSMCs), which contribute to important cellular functions. We have previously shown that PKC is obligat...
Autores principales: | Shi, Jian, Miralles, Francesc, Birnbaumer, Lutz, Large, William A., Albert, Anthony P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714548/ https://www.ncbi.nlm.nih.gov/pubmed/26467792 http://dx.doi.org/10.1096/fj.15-280271 |
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