Reversible Fluoxetine-Induced Hyperthyroidism: A Case Report

BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) are typically used as antidepressants. Clinically significant SSRI-induced thyroid dysfunction is rare. CASE: We report a case of hyperthyroidism induced by fluoxetine in a female patient with major depressive disorder. Her thyroid profiles...

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Detalles Bibliográficos
Autores principales: Lai, Jianbo, Xu, Dongrong, Peterson, Bradley S., Xu, Yi, Wei, Ning, Zhang, Minming, Hu, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714632/
https://www.ncbi.nlm.nih.gov/pubmed/26626429
http://dx.doi.org/10.1097/WNF.0000000000000116
Descripción
Sumario:BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) are typically used as antidepressants. Clinically significant SSRI-induced thyroid dysfunction is rare. CASE: We report a case of hyperthyroidism induced by fluoxetine in a female patient with major depressive disorder. Her thyroid profiles indicated hyperthyroidism after a 10-week treatment with fluoxetine and were restored after discontinuation of fluoxetine and administration with venlafaxine. In the first year of follow-up, her thyroid functions as well as her depressive symptoms remained perfectly normal. CONCLUSIONS: This case highlights the necessity of monitoring thyroid profiles during SSRI treatment.

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