Direct regulation of transforming growth factor β‐induced epithelial–mesenchymal transition by the protein phosphatase activity of unphosphorylated PTEN in lung cancer cells

Transforming growth factor β (TGFβ) causes the acquisition of epithelial–mesenchymal transition (EMT). Although the tumor suppressor gene PTEN (phosphatase and tensin homologue deleted from chromosome 10) can negatively regulate many signaling pathways activated by TGFβ, hyperactivation of these sig...

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Detalles Bibliográficos
Autores principales: Kusunose, Masaaki, Hashimoto, Naozumi, Kimura, Motohiro, Ogata, Ryo, Aoyama, Daisuke, Sakamoto, Koji, Miyazaki, Shinichi, Ando, Akira, Omote, Norihito, Imaizumi, Kazuyoshi, Kawabe, Tsutomu, Hasegawa, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714667/
https://www.ncbi.nlm.nih.gov/pubmed/26450531
http://dx.doi.org/10.1111/cas.12831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714667/
https://www.ncbi.nlm.nih.gov/pubmed/26450531
http://dx.doi.org/10.1111/cas.12831

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