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Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruzi
The molecular mechanisms of Trypanosoma cruzi induced cardiac fibrosis remains to be elucidated. Primary human cardiomyoctes (PHCM) exposed to invasive T. cruzi trypomastigotes were used for transcriptome profiling and downstream bioinformatic analysis to determine fibrotic-associated genes regulate...
Autores principales: | Udoko, Aniekanabassi N., Johnson, Candice A., Dykan, Andrey, Rachakonda, Girish, Villalta, Fernando, Mandape, Sammed N., Lima, Maria F., Pratap, Siddharth, Nde, Pius N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714843/ https://www.ncbi.nlm.nih.gov/pubmed/26771187 http://dx.doi.org/10.1371/journal.pntd.0003747 |
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