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Urotensin-ⅡReceptor Antagonist SB-710411 Protects Rat Heart against Ischemia-Reperfusion Injury via RhoA/ROCK Pathway

AIM: SB-710411 is a rat selective urotensin-II (U-II) receptor antagonist, which can block U-II-induced contraction of the aorta and inhibit U-II-induced myocardial fibrosis in rats. However, the effect of SB-710411 on myocardial ischemia-reperfusion (I/R) injury is unclear. The present study was de...

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Detalles Bibliográficos
Autores principales:	Luo, Sheng-Yong, Chen, Shuo, Qin, Yi-De, Chen, Zhi-Wu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714846/ https://www.ncbi.nlm.nih.gov/pubmed/26771557 http://dx.doi.org/10.1371/journal.pone.0146094

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