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Efficacy of Rifampin Plus Clofazimine in a Murine Model of Mycobacterium ulcerans Disease
Treatment of Buruli ulcer, or Mycobacterium ulcerans disease, has shifted from surgical excision and skin grafting to antibiotic therapy usually with 8 weeks of daily rifampin (RIF) and streptomycin (STR). Although the results have been highly favorable, administration of STR requires intramuscular...
Autores principales: | Converse, Paul J., Tyagi, Sandeep, Xing, Yalan, Li, Si-Yang, Kishi, Yoshito, Adamson, John, Nuermberger, Eric L., Grosset, Jacques H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714850/ https://www.ncbi.nlm.nih.gov/pubmed/26042792 http://dx.doi.org/10.1371/journal.pntd.0003823 |
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