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The Neuroprotective Effect of Rapamycin as a Modulator of the mTOR-NF-κB Axis during Retinal Inflammation

PURPOSE: The determination of the molecular mechanism underlying retinal pathogenesis and visual dysfunction during innate inflammation, and the treatment effect of rapamycin thereon. METHODS: The endotoxin-induced uveitis and retinitis mouse model was established by injecting lipopolysaccharide. Th...

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Detalles Bibliográficos
Autores principales:	Okamoto, Tomohiro, Ozawa, Yoko, Kamoshita, Mamoru, Osada, Hideto, Toda, Eriko, Kurihara, Toshihide, Nagai, Norihiro, Umezawa, Kazuo, Tsubota, Kazuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714903/ https://www.ncbi.nlm.nih.gov/pubmed/26771918 http://dx.doi.org/10.1371/journal.pone.0146517

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