Discovery of Influenza A Virus Sequence Pairs and Their Combinations for Simultaneous Heterosubtypic Targeting that Hedge against Antiviral Resistance

The multiple circulating human influenza A virus subtypes coupled with the perpetual genomic mutations and segment reassortment events challenge the development of effective therapeutics. The capacity to drug most RNAs motivates the investigation on viral RNA targets. 123,060 segment sequences from...

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Detalles Bibliográficos
Autores principales: Wee, Keng Boon, Lee, Raphael Tze Chuen, Lin, Jing, Pramono, Zacharias Aloysius Dwi, Maurer-Stroh, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714944/
https://www.ncbi.nlm.nih.gov/pubmed/26771381
http://dx.doi.org/10.1371/journal.pcbi.1004663

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