Cargando…
Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoires
Processes that define immunoglobulin repertoires are commonly presumed to be the same for all murine B cells. However, studies here that couple high-dimensional FACS sorting with large-scale quantitative IgH deep-sequencing demonstrate that B-1a IgH repertoire differs dramatically from the follicula...
Autores principales: | Yang, Yang, Wang, Chunlin, Yang, Qunying, Kantor, Aaron B, Chu, Hiutung, Ghosn, Eliver EB, Qin, Guang, Mazmanian, Sarkis K, Han, Jian, Herzenberg, Leonore A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714975/ https://www.ncbi.nlm.nih.gov/pubmed/26422511 http://dx.doi.org/10.7554/eLife.09083 |
Ejemplares similares
-
Development of B Cells and Erythrocytes Is Specifically Impaired by the Drug Celastrol in Mice
por: Kusy, Sophie, et al.
Publicado: (2012) -
IMMUNOGLOBULIN ISOANTIGENS (ALLOTYPES) IN THE MOUSE : I. GENETICS AND CROSS-REACTIONS OF THE 7S γ(2A)-ISOANTIGENS CONTROLLED BY ALLELES AT THE IG-1 LOCUS
por: Herzenberg, Leonard A., et al.
Publicado: (1965) -
Different B cell subpopulations show distinct patterns in their IgH repertoire metrics
por: Ghraichy, Marie, et al.
Publicado: (2021) -
Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci
por: Inlay, Matthew A., et al.
Publicado: (2006) -
Submicroscopic Deletions of Immunoglobulin Heavy Chain Gene (IGH) in Precursor B Lymphoblastic Leukemia with IGH Rearrangements
por: Huh, Jungwon, et al.
Publicado: (2015)