SB203580 increases G-CSF production via a stem-loop destabilizing element in the 3’ untranslated region in macrophages independently of its effect on p38 MAPK activity

BACKGROUND: Granulocyte-colony stimulating factor (G-CSF) is a major regulator of the production and survival of neutrophils. Regulation of G-CSF expression is complex and occurs at both transcription and post-transcription levels. Two distinct types of cis-acting elements in the 3’ untranslated reg...

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Detalles Bibliográficos
Autores principales: Chang, Shwu-Fen, Li, Huai-Ci, Huang, Yu-Pei, Tasi, Wen-Ju, Chou, Yuan-Yi, Lu, Shao-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715298/
https://www.ncbi.nlm.nih.gov/pubmed/26772539
http://dx.doi.org/10.1186/s12929-016-0221-z

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