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Survival from skin cancer and its associated factors in Kurdistan province of Iran
Background: We explored survival of skin cancer and its determinants in Kurdistan province of Iran. Methods: In a retrospective cohort design, we identified all registered skin cancer patients in Kurdistan Cancer Registry from year 2000 to 2009. Information on time and cause of death were obtained f...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Iran University of Medical Sciences
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715398/ https://www.ncbi.nlm.nih.gov/pubmed/26793668 |
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author | Ahmadi, Galavizh Asadi-Lari, Mohsen Amani, Saeid Solaymani-Dodaran, Masoud |
author_facet | Ahmadi, Galavizh Asadi-Lari, Mohsen Amani, Saeid Solaymani-Dodaran, Masoud |
author_sort | Ahmadi, Galavizh |
collection | PubMed |
description | Background: We explored survival of skin cancer and its determinants in Kurdistan province of Iran. Methods: In a retrospective cohort design, we identified all registered skin cancer patients in Kurdistan Cancer Registry from year 2000 to 2009. Information on time and cause of death were obtained from Registrar’s office and information on type, stage and anatomic locations were extracted from patients’ hospital records. Additional demographic information was collected via a telephone interview. We calculated the 3 and 5 years survival. Survival experiences in different groups were compared using log rank test. Cox proportional hazard model was built and hazard ratios and their 95% confidence intervals were calculated. Results: Of a total of 1353, contact information for 667 patients were available, all of which were followed up. 472 telephone interviews were conducted. Mean follow-up time was 34 months. We identified 78 deaths in this group of patients and 44 of them were because of skin cancer. After controlling for confounding, tumour type, anatomical location, and diseases stage remained significantly associated with survival. Hazard ratios for death because of squamous cell carcinoma was 74.5 (95%CI: 4.8-1146) and for melanoma was 24.4 (95%CI: 1.3-485) compared with basal cell carcinomas. Hazard ratio for tumours in stage 4 was 16.7 (95%CI: 1.8-156.6) and for stage 3 was 16.8 (95%CI: 1.07-260) compared with stage 1 and 2. Conclusion: Tumour stage is independently associated with survival. Relatively low survival rates suggest delayed diagnosis. Increasing public awareness through media about the warning signs of skin cancers could increase the chance of survival in these patients. |
format | Online Article Text |
id | pubmed-4715398 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Iran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-47153982016-01-20 Survival from skin cancer and its associated factors in Kurdistan province of Iran Ahmadi, Galavizh Asadi-Lari, Mohsen Amani, Saeid Solaymani-Dodaran, Masoud Med J Islam Repub Iran Original Article Background: We explored survival of skin cancer and its determinants in Kurdistan province of Iran. Methods: In a retrospective cohort design, we identified all registered skin cancer patients in Kurdistan Cancer Registry from year 2000 to 2009. Information on time and cause of death were obtained from Registrar’s office and information on type, stage and anatomic locations were extracted from patients’ hospital records. Additional demographic information was collected via a telephone interview. We calculated the 3 and 5 years survival. Survival experiences in different groups were compared using log rank test. Cox proportional hazard model was built and hazard ratios and their 95% confidence intervals were calculated. Results: Of a total of 1353, contact information for 667 patients were available, all of which were followed up. 472 telephone interviews were conducted. Mean follow-up time was 34 months. We identified 78 deaths in this group of patients and 44 of them were because of skin cancer. After controlling for confounding, tumour type, anatomical location, and diseases stage remained significantly associated with survival. Hazard ratios for death because of squamous cell carcinoma was 74.5 (95%CI: 4.8-1146) and for melanoma was 24.4 (95%CI: 1.3-485) compared with basal cell carcinomas. Hazard ratio for tumours in stage 4 was 16.7 (95%CI: 1.8-156.6) and for stage 3 was 16.8 (95%CI: 1.07-260) compared with stage 1 and 2. Conclusion: Tumour stage is independently associated with survival. Relatively low survival rates suggest delayed diagnosis. Increasing public awareness through media about the warning signs of skin cancers could increase the chance of survival in these patients. Iran University of Medical Sciences 2015-10-12 /pmc/articles/PMC4715398/ /pubmed/26793668 Text en © 2015 Iran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Original Article Ahmadi, Galavizh Asadi-Lari, Mohsen Amani, Saeid Solaymani-Dodaran, Masoud Survival from skin cancer and its associated factors in Kurdistan province of Iran |
title | Survival from skin cancer and its associated factors in Kurdistan province of Iran |
title_full | Survival from skin cancer and its associated factors in Kurdistan province of Iran |
title_fullStr | Survival from skin cancer and its associated factors in Kurdistan province of Iran |
title_full_unstemmed | Survival from skin cancer and its associated factors in Kurdistan province of Iran |
title_short | Survival from skin cancer and its associated factors in Kurdistan province of Iran |
title_sort | survival from skin cancer and its associated factors in kurdistan province of iran |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715398/ https://www.ncbi.nlm.nih.gov/pubmed/26793668 |
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