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Relationship between esophageal clinical symptoms and manometry findings in patients with esophageal motility disorders: a cross-sectional study
Background: Manometry is the gold-standard diagnostic test for motility disorders in the esophagus. The development of high-resolution manometry catheters and software displays of manometry recordings in color-coded pressure plots have changed the diagnostic assessment of esophageal disease. The dia...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Iran University of Medical Sciences
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715411/ https://www.ncbi.nlm.nih.gov/pubmed/26793662 |
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author | FakhreYaseri, Hashem FakhreYaseri, Ali Mohammad Baradaran Moghaddam, Ali Soltani Arabshhi, Seyed Kamran |
author_facet | FakhreYaseri, Hashem FakhreYaseri, Ali Mohammad Baradaran Moghaddam, Ali Soltani Arabshhi, Seyed Kamran |
author_sort | FakhreYaseri, Hashem |
collection | PubMed |
description | Background: Manometry is the gold-standard diagnostic test for motility disorders in the esophagus. The development of high-resolution manometry catheters and software displays of manometry recordings in color-coded pressure plots have changed the diagnostic assessment of esophageal disease. The diagnostic value of particular esophageal clinical symptoms among patients suspected of esophageal motor disorders (EMDs) is still unknown. The aim of this study was to explore the sensitivity, specificity, and predictive accuracy of presenting esophageal symptoms between abnormal and normal esophageal manometry findings. Methods: We conducted a cross-sectional study of 623 patients aged 11-80 years. Data were collected from clinical examinations as well as patient questionnaires. The sensitivity, specificity, and accuracy were calculated after high-resolution manometry plots were reviewed according to the most recent Chicago Criteria. Results: The clinical symptoms were not sensitive enough to discriminate between EMDs. Nevertheless, dysphagia, noncardiac chest pain, hoarseness, vomiting, and weight loss had high specificity and high accuracy to distinguish EMDs from normal findings. Regurgitation and heartburn did not have good accuracy for the diagnosis of EMDs. Conclusion: Clinical symptoms are not reliable enough to discriminate between EMDs. Clinical symptoms can, however, discriminate between normal findings and EMDs, especially achalasia. |
format | Online Article Text |
id | pubmed-4715411 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Iran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-47154112016-01-20 Relationship between esophageal clinical symptoms and manometry findings in patients with esophageal motility disorders: a cross-sectional study FakhreYaseri, Hashem FakhreYaseri, Ali Mohammad Baradaran Moghaddam, Ali Soltani Arabshhi, Seyed Kamran Med J Islam Repub Iran Original Article Background: Manometry is the gold-standard diagnostic test for motility disorders in the esophagus. The development of high-resolution manometry catheters and software displays of manometry recordings in color-coded pressure plots have changed the diagnostic assessment of esophageal disease. The diagnostic value of particular esophageal clinical symptoms among patients suspected of esophageal motor disorders (EMDs) is still unknown. The aim of this study was to explore the sensitivity, specificity, and predictive accuracy of presenting esophageal symptoms between abnormal and normal esophageal manometry findings. Methods: We conducted a cross-sectional study of 623 patients aged 11-80 years. Data were collected from clinical examinations as well as patient questionnaires. The sensitivity, specificity, and accuracy were calculated after high-resolution manometry plots were reviewed according to the most recent Chicago Criteria. Results: The clinical symptoms were not sensitive enough to discriminate between EMDs. Nevertheless, dysphagia, noncardiac chest pain, hoarseness, vomiting, and weight loss had high specificity and high accuracy to distinguish EMDs from normal findings. Regurgitation and heartburn did not have good accuracy for the diagnosis of EMDs. Conclusion: Clinical symptoms are not reliable enough to discriminate between EMDs. Clinical symptoms can, however, discriminate between normal findings and EMDs, especially achalasia. Iran University of Medical Sciences 2015-10-03 /pmc/articles/PMC4715411/ /pubmed/26793662 Text en © 2015 Iran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Original Article FakhreYaseri, Hashem FakhreYaseri, Ali Mohammad Baradaran Moghaddam, Ali Soltani Arabshhi, Seyed Kamran Relationship between esophageal clinical symptoms and manometry findings in patients with esophageal motility disorders: a cross-sectional study |
title | Relationship between esophageal clinical symptoms and manometry findings in patients with esophageal motility disorders: a cross-sectional study |
title_full | Relationship between esophageal clinical symptoms and manometry findings in patients with esophageal motility disorders: a cross-sectional study |
title_fullStr | Relationship between esophageal clinical symptoms and manometry findings in patients with esophageal motility disorders: a cross-sectional study |
title_full_unstemmed | Relationship between esophageal clinical symptoms and manometry findings in patients with esophageal motility disorders: a cross-sectional study |
title_short | Relationship between esophageal clinical symptoms and manometry findings in patients with esophageal motility disorders: a cross-sectional study |
title_sort | relationship between esophageal clinical symptoms and manometry findings in patients with esophageal motility disorders: a cross-sectional study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715411/ https://www.ncbi.nlm.nih.gov/pubmed/26793662 |
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