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Mammalian target of rapamycin inhibition in polycystic kidney disease: From bench to bedside

Autosomal dominant polycystic kidney disease (ADPKD) is the most common life-threatening hereditary disease in the USA resulting in chronic kidney disease and the need for dialysis and transplantation. Approximately 85% of cases of ADPKD are caused by a mutation in the Pkd1 gene that encodes polycys...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Jung, Edelstein, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716095/
https://www.ncbi.nlm.nih.gov/pubmed/26894018
http://dx.doi.org/10.1016/j.krcp.2012.07.002