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Mammalian target of rapamycin inhibition in polycystic kidney disease: From bench to bedside
Autosomal dominant polycystic kidney disease (ADPKD) is the most common life-threatening hereditary disease in the USA resulting in chronic kidney disease and the need for dialysis and transplantation. Approximately 85% of cases of ADPKD are caused by a mutation in the Pkd1 gene that encodes polycys...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716095/ https://www.ncbi.nlm.nih.gov/pubmed/26894018 http://dx.doi.org/10.1016/j.krcp.2012.07.002 |