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Ubiquitin-Mediated Degradation of Aurora Kinases

The Aurora kinases are essential regulators of mitosis in eukaryotes. In somatic cell divisions of higher eukaryotes, the paralogs Aurora kinase A (AurA) and Aurora kinase B (AurB) play non-overlapping roles that depend on their distinct spatiotemporal activities. These mitotic roles of Aurora kinas...

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Detalles Bibliográficos
Autores principales:	Lindon, Catherine, Grant, Rhys, Min, Mingwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716142/ https://www.ncbi.nlm.nih.gov/pubmed/26835416 http://dx.doi.org/10.3389/fonc.2015.00307

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