Aristolochic acid exposure in Romania and implications for renal cell carcinoma

BACKGROUND: Aristolochic acid (AA) is a nephrotoxicant associated with AA nephropathy (AAN) and upper urothelial tract cancer (UUTC). Whole-genome sequences of 14 Romanian cases of renal cell carcinoma (RCC) recently exhibited mutational signatures consistent with AA exposure, although RCC had not b...

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Detalles Bibliográficos
Autores principales: Turesky, Robert J, Yun, Byeong Hwa, Brennan, Paul, Mates, Dana, Jinga, Viorel, Harnden, Patricia, Banks, Rosamonde E, Blanche, Helene, Bihoreau, Marie-Therese, Chopard, Priscilia, Letourneau, Louis, Lathrop, G Mark, Scelo, Ghislaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716534/
https://www.ncbi.nlm.nih.gov/pubmed/26657656
http://dx.doi.org/10.1038/bjc.2015.402

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