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Melanoma-expressed CD70 is involved in invasion and metastasis

BACKGROUND: CD70 is a costimulatory molecule of the tumour necrosis factor family expressed in activated immune cells and some solid tumours. In lymphocytes CD70 triggers T cell-mediated cytotoxicity and mitogen-activated protein kinase phosphorylation. METHODS: We evaluated the expression of CD70 i...

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Detalles Bibliográficos
Autores principales: Pich, Christine, Sarrabayrouse, Guillaume, Teiti, Iotefa, Mariamé, Bernard, Rochaix, Philippe, Lamant, Laurence, Favre, Gilles, Maisongrosse, Véronique, Tilkin-Mariamé, Anne-Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716537/
https://www.ncbi.nlm.nih.gov/pubmed/26671750
http://dx.doi.org/10.1038/bjc.2015.412