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Electroacupuncture protects against ischemic stroke by reducing autophagosome formation and inhibiting autophagy through the mTORC1-ULK1 complex-Beclin1 pathway

In a previous study by our group, we demonstrated that electroacupuncture (EA) activates the class I phosphoinositide 3-kinase (PI3K)/Akt signaling pathway. There is considerable evidence that the downstream mammalian target of rapamycin complex 1 (mTORC1) plays an important role in autophagy follow...

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Detalles Bibliográficos
Autores principales: LIU, WEILIN, SHANG, GUANHAO, YANG, SHANLI, HUANG, JIA, XUE, XIEHUA, LIN, YUNJIAO, ZHENG, YI, WANG, XIAN, WANG, LULU, LIN, RUHUI, TAO, JING, CHEN, LIDIAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716798/
https://www.ncbi.nlm.nih.gov/pubmed/26647915
http://dx.doi.org/10.3892/ijmm.2015.2425

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