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Receptor-Interacting Protein Kinase-2 Inhibition by CYLD Impairs Antibacterial Immune Responses in Macrophages

Upon infection with intracellular bacteria, nucleotide oligomerization domain protein 2 recognizes bacterial muramyl dipeptide and binds, subsequently, to receptor-interacting serine/threonine kinase 2 (RIPK2), which activates immune responses via the nuclear factor kappa-light-chain enhancer of act...

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Detalles Bibliográficos
Autores principales:	Wex, Katharina, Schmid, Ursula, Just, Sissy, Wang, Xu, Wurm, Rebecca, Naumann, Michael, Schlüter, Dirk, Nishanth, Gopala
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717182/ https://www.ncbi.nlm.nih.gov/pubmed/26834734 http://dx.doi.org/10.3389/fimmu.2015.00650

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