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IL-22-Expressing Murine Lymphocytes Display Plasticity and Pathogenicity in Reporter Mice
IL-22 has multiple activities ranging from tissue repair to inflammation. To characterize the pathogenicity and plasticity of cells that produce IL-22, a novel reporter mouse strain was generated. Homeostatic IL-22 reporter expression was observed in intestinal lymphoid cells identified as CD4 T cel...
Autores principales: | Shen, Wei, Hixon, Julie A., McLean, Mairi H., Li, Wen Qing, Durum, Scott K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717188/ https://www.ncbi.nlm.nih.gov/pubmed/26834739 http://dx.doi.org/10.3389/fimmu.2015.00662 |
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