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Using measures of single‐cell physiology and physiological state to understand organismic aging

Genetically identical organisms in homogeneous environments have different lifespans and healthspans. These differences are often attributed to stochastic events, such as mutations and ‘epimutations’, changes in DNA methylation and chromatin that change gene function and expression. But work in the...

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Detalles Bibliográficos
Autores principales: Mendenhall, Alexander, Driscoll, Monica, Brent, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717262/
https://www.ncbi.nlm.nih.gov/pubmed/26616110
http://dx.doi.org/10.1111/acel.12424