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Effects of 2‐year calorie restriction on circulating levels of IGF‐1, IGF‐binding proteins and cortisol in nonobese men and women: a randomized clinical trial

Young‐onset calorie restriction (CR) in rodents decreases serum IGF‐1 concentration and increases serum corticosterone levels, which have been hypothesized to play major roles in mediating its anticancer and anti‐aging effects. However, little is known on the effects of CR on the IGF‐1 system and co...

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Detalles Bibliográficos
Autores principales: Fontana, Luigi, Villareal, Dennis T., Das, Sai K., Smith, Steven R., Meydani, Simin N., Pittas, Anastassios G., Klein, Samuel, Bhapkar, Manjushri, Rochon, James, Ravussin, Eric, Holloszy, John O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717266/
https://www.ncbi.nlm.nih.gov/pubmed/26443692
http://dx.doi.org/10.1111/acel.12400