Age‐associated changes in long‐chain fatty acid profile during healthy aging promote pro‐inflammatory monocyte polarization via PPARγ

Differences in lipid metabolism associate with age‐related disease development and lifespan. Inflammation is a common link between metabolic dysregulation and aging. Saturated fatty acids (FAs) initiate pro‐inflammatory signalling from many cells including monocytes; however, no existing studies hav...

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Detalles Bibliográficos
Autores principales: Pararasa, Chathyan, Ikwuobe, John, Shigdar, Shahjahan, Boukouvalas, Alexis, Nabney, Ian T., Brown, James E., Devitt, Andrew, Bailey, Clifford J., Bennett, Stuart J., Griffiths, Helen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717269/
https://www.ncbi.nlm.nih.gov/pubmed/26522807
http://dx.doi.org/10.1111/acel.12416

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