Cargando…
Age modifies respiratory complex I and protein homeostasis in a muscle type‐specific manner
Changes in mitochondrial function with age vary between different muscle types, and mechanisms underlying this variation remain poorly defined. We examined whether the rate of mitochondrial protein turnover contributes to this variation. Using heavy label proteomics, we measured mitochondrial protei...
Autores principales: | Kruse, Shane E., Karunadharma, Pabalu P., Basisty, Nathan, Johnson, Richard, Beyer, Richard P., MacCoss, Michael J., Rabinovitch, Peter S., Marcinek, David J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717270/ https://www.ncbi.nlm.nih.gov/pubmed/26498839 http://dx.doi.org/10.1111/acel.12412 |
Ejemplares similares
-
Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects
por: Karunadharma, Pabalu P, et al.
Publicado: (2015) -
Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart
por: Dai, Dao-Fu, et al.
Publicado: (2014) -
Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts
por: Chiao, Ying Ann, et al.
Publicado: (2016) -
Mitochondrial‐targeted catalase is good for the old mouse proteome, but not for the young: ‘reverse’ antagonistic pleiotropy?
por: Basisty, Nathan, et al.
Publicado: (2016) -
Elamipretide effects on the skeletal muscle phosphoproteome in aged female mice
por: Campbell, Matthew D., et al.
Publicado: (2022)