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The Immp2l mutation causes age‐dependent degeneration of cerebellar granule neurons prevented by antioxidant treatment
Reactive oxygen species are implicated in age‐associated neurodegeneration, although direct in vivo evidence is lacking. We recently showed that mice with a mutation in the Inner Mitochondrial Membrane Peptidase 2‐like (Immp2l) gene had elevated levels of mitochondrial superoxide, impaired fertility...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717271/ https://www.ncbi.nlm.nih.gov/pubmed/26616244 http://dx.doi.org/10.1111/acel.12426 |