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Sex‐ and tissue‐specific changes in mTOR signaling with age in C57BL/6J mice

Inhibition of the mTOR (mechanistic Target Of Rapamycin) signaling pathway robustly extends the lifespan of model organisms including mice. The precise molecular mechanisms and physiological effects that underlie the beneficial effects of rapamycin are an exciting area of research. Surprisingly, whi...

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Detalles Bibliográficos
Autores principales:	Baar, Emma L., Carbajal, Kathryn A., Ong, Irene M., Lamming, Dudley W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717274/ https://www.ncbi.nlm.nih.gov/pubmed/26695882 http://dx.doi.org/10.1111/acel.12425

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