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Reduction of fibroblast size/mechanical force down‐regulates TGF‐β type II receptor: implications for human skin aging
The structural integrity of human skin is largely dependent on the quality of the dermal extracellular matrix (ECM), which is produced, organized, and maintained by dermal fibroblasts. Normally, fibroblasts attach to the ECM and thereby achieve stretched, elongated morphology. A prominent characteri...
Autores principales: | Fisher, Gary J., Shao, Yuan, He, Tianyuan, Qin, Zhaoping, Perry, Daniel, Voorhees, John J., Quan, Taihao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717276/ https://www.ncbi.nlm.nih.gov/pubmed/26780887 http://dx.doi.org/10.1111/acel.12410 |
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