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Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study
OBJECTIVES: A recent study identified 16 genetic variants associated with N-glycosylation of human IgG. Several of the genomic regions where these single nucleotide polymorphisms (SNPs) reside have also been associated with autoimmune disease (AID) susceptibility, suggesting there may be pleiotropy...
Autores principales: | Yarwood, Annie, Viatte, Sebastien, Okada, Yukinori, Plenge, Robert, Yamamoto, Kazuhiko, Barton, Anne, Symmons, Deborah, Raychaudhuri, Soumya, Klareskog, Lars, Gregersen, Peter, Worthington, Jane, Eyre, Steve |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717396/ https://www.ncbi.nlm.nih.gov/pubmed/26386125 http://dx.doi.org/10.1136/annrheumdis-2014-207210 |
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