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α-Carboline derivative TJY-16 inhibits tumor growth by inducing G2/M cell cycle arrest in glioma cells

BACKGROUND: Glioblastoma multiforme (GBM) is the most lethal primary brain tumors which remains difficult to cure despite advances in surgery, radiotherapy and chemotherapy. Therefore, the development of new drug is urgently needed. α-carboline derivatives were usually isolated from marine animals s...

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Detalles Bibliográficos
Autores principales: Huang, Hsiao-Chieh, Liu, Wei-Ting, Hua, Kuo-Su, Hung, Hui-Chi, Tsai, Jui-Ying, Kuo, Sheng-Chu, Huang, Li-Jiau, Gean, Po-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717554/
https://www.ncbi.nlm.nih.gov/pubmed/26786523
http://dx.doi.org/10.1186/s12929-016-0222-y

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