A surgical approach in the treatment of preputial gland abscesses in mice

BACKGROUND: Preputial gland infection is a common occurrence in non-breeder male mice and can lead to abscesses. This report describes a surgical approach to treating and preventing this condition. RESULTS: Surgical removal of the glands was undertaken in 258 male C3H/HeNHsd mice. The glands were su...

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Detalles Bibliográficos
Autores principales: Bertrand, Henri G. M. J., Thomas, Aurelie A., Ellen, Yvette C., Dorward, Robert S., Flecknell, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717595/
https://www.ncbi.nlm.nih.gov/pubmed/26785639
http://dx.doi.org/10.1186/s12917-016-0636-5
Descripción
Sumario:BACKGROUND: Preputial gland infection is a common occurrence in non-breeder male mice and can lead to abscesses. This report describes a surgical approach to treating and preventing this condition. RESULTS: Surgical removal of the glands was undertaken in 258 male C3H/HeNHsd mice. The glands were successfully removed in all of the animals with a low rate of post-surgery complications. Abscess recurrence due to incomplete gland resection occurred in 2.3 % of animals. Surgical wound opening (3.1 %) and infection of the surgical site (2.3 %) also occurred but were treated successfully. CONCLUSION: In the study described here, early intervention was successful in preventing intercurrent infection compromising both animal welfare and the outcome of the study.

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